Home
Cancer Chemotherapy
Chemotherapy Drug
Chemotherapy Information
Chemotherapy Patients
Type 1 Of Chemotherapy
Type 2 Of Chemotherapy
Site Map
Carboplatin+Paclitaxel+surgery clin. trial experience

I'm posting for a friend who was recently diagnosed w/ stage II adenocarinoma of the lung. Her physicians have recommended that she enter a trial - SWOG-S9900 - which will evaluate chemo administered pre-surgery vs. chemo administered post-surgery. We would be interested in hearing from anyone who has participated in this trial, or has anything else to say about this drug regimen or this disease, any good links to check out,


---------------------

Carboplatin has been the mainstay of lung cancer chemotherapy and paxlitaxel has been showing some good results. An oncologist friend indicated that carboplatin and paclitaxel are the favored combination though the literature and the nci website shows a variety of others. We can say with relative certainty that mult-modal chemotherapy, use of various drugs, achieves better results than a particular drug. Which combination achieves the best results remains to be seen.

I cannot give you advice but I would have mixed feelings about a clinical trial for a stage 2 patient. At stage 4 (advanced metastatic cancer) the argument for participation is clearer, we do not know what works so some experimentation could be helpful. Stage 2 does have a particular program. That said, it is not clear whether pre-surgery chemo is better. I would ask your doctor, rather than participating in this trial, shouldn't I simply get the treatment that you think is best. His answer may be that he believes pre-surgery chemotherapy could be helpful, but he cannot provide it outside a clinical setting, since it remains experimental. Hope this helps.
(I am not a doctor, but I am completing a book on lung cancer.)

 


Submit your comment or answer