-Chemotherapy can damage the ovaries and reduce their level of hormone production. As a result, some young women will go through menopause after having chemotherapy and others may become temporarily or permanently infertile. Your sister should consult a fertility specialist to determine what her options might be if she wants another baby.

-Vritually all chemotherapy agents are cytoxic, and they are most cytoxic to rapidly dividing cells, such as the epitheleal tissues and the reproductive tract. Most are also known teratogens. If you add radiothearpy to the equation, if further increases the chances of infertility.

I would question the intelligence of any physician who didn't warn a chemo therapy survivors of both the high probability of infertility, as well as the greatly increased risk of fetal deformities.

-There is a high risk of fetal abnormality if chemo or radiation is given during the first trimester. There is no good evidence of increased risk of fetal abnormalities in a woman who gets pregnant AFTER treatment has finished. So stop the scare stories.