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Chemotherapy treatment for Brain Metastases and Breast Cancer tumor

My mom was diagnozed with Brain Metastases the other day. She had a breast cancer 1.5 years ago - one of her breasts was totally removed and she seemed to be alright after that. A week ago, however, she began having headaches and nausea. The brain scan showed a wide-spread tumor that doctors seem to agree it moved from her breast. She's about to start her radio in a week, followed by a chemo.

What are the best chemo drugs available for her condition ? What are her chances of survival ?


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-The treatment for the brain mets is the radiotherapy, as chemo does not get into the brain very well. The chemo is because patients with brain mets almost always have disease i other parts of the body.

The median survival for a patient with brain mets due to breast cancer is about 4-5 months. This is median, though, which means that half the patients do better, and half do worse.

-There is no good answer to the treatment of widespread metastatic lesions. I would defer a decision on chemotherapy until after your mom has had her radiation therapy. The taxanes will cross the blood--brain barrier and are active in breast cancer.

-Some say that the best available treatment for brain tumors today are not conventional chemo agents (which experience problems getting past the blood-brain barrier) but may be Stanislaw Burzynski's "antineoplastons". Since these as I understand it are synthetic molecules similar to ones produced by the body for the purpose of repairing altered cells, they may suffer less from this problem. In any case, Burzynski reportedly has the best statistics for patient outcomes with brain tumors. Also, Burzynski reports in at least one case that he has observed perfect reconstruction of normal, functional brain tissue at the site of the former tumor.

 


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